Vol. 77, March 2009

Changes in Molecular Size and Shape of Hemoglobin of Systemic Lupus Erythermatosus

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Changes in Molecular Size and Shape of Hemoglobin of Systemic Lupus Erythermatosus,SAMIR W. AZIZ, BASSEM M. RAFAAT, NAHED S. HASAN and AHMED HANAFY

 

Abstract
Different hemoglobin derivatives concentration and elec-trical conductivity were measured for patients suffered from, in addition the dielectric relaxation in the frequency range 100KHz up to 10MHz of Hb molecule of systemic lupus patients compared to normal control. Abnormal dynamic motion of Hb was found, a lack of changes in the size and/or shape of Hb. Also, the dielectric results indicating that the molecular shape tends to deviate from the spherical form as the activity (severity) of the disease increases.

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