Obesity and its Relationship with Glycemic Control in Type-2 Diabetes,HASSAN A.E. ABDELWAHID and NADIA M. MANSOUR
Abstract
Background: Obesity is central to the development of insulin resistance, leading to type 2 diabetes and cardiovascular disease, among other serious medical conditions. In patients with type 2 diabetes, the benefits of weight loss include both improved overall glycemic control and cardiovascular disease risk profile.
Aim: The aim of the present work was to study the pattern of overweight and obesity in type-2 diabetes. The Specific objectives included determination of the prevalence of the overweight and obesity among type-2 diabetes and assessment of their effects on the glycemic control.
Methods: A cross sectional design was used. The target population was type-2 diabetic patients in Ismailia City, Egypt. The study population was type-2 diabetics attending the family medicine clinic in Ismailia University hospital. The study included 220 type-2 diabetics who were screened for over-weight and obesity.
Results: The present study illustrates that, only 14.5% of type-2 diabetics had BMI within the normal range, (35% of male patients and 8% of female patients), while 45.9% were overweight; the percentage of overweight male patients was higher (50%) than female patients (45%). Obesity was found in 39.5% of the patients (15% of the male and 47% of the female patients). Extreme obesity was detected only in females (18%). The glycosylated hemoglobin (g %) of overweight (11.5±2.7) was significantly different from that of the obese patients (13.2±3.6). The study demonstrates, also, that fasting blood sugar (mg/dL) of diabetic patients with normal BMI (155.9±70.5) was significantly different from each of the overweight (227.5±87.7) and obese diabetics (210.9± 79.9).
Conclusion: Overweight and obesity are highly prevalent in type-2 diabetics. Also increase in the BMI is associated with poor glycemic control. These findings signify life style modifications that are immensely needed to decrease the bodyweight and improve the glycemic control.