Helicobacter Pylori Infection in Children with Growth Failure
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- Category: Vol. 77, September 2009
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Helicobacter Pylori Infection in Children with Growth Failure, MONA R. NASR, RAMADAN A. RAMADAN, HANY BOTROS, HUSSEIN MAHDY and MANAL S. RAMADAN
Abstract
Objective: To examine if helicobacter pylori infection has a role in growth failure in children.
Patients and Methods: 26 children patients with growth failure and 14 normally growing children of the same age group, socioeconomic level and sex ratio as controls were included in the study. All were subjected to full history taking, clinical examination, anthropometry, laboratory investigations and upper endoscopy with gastric biopsy taking for diagnosis of helicobacter pylori infection by histopathology. Positive cases for helicobacter pylori infection were treated by eradi-cation therapy; the group of children with growth failure were followed for 6 months and reevaluated.
Results: Helicobacter pylori infection was diagnosed in 77% of children with growth failure, while it was diagnosed in 43% of normal children (p<0.05). After 6 months of erad-ication therapy, there was significant increase in height, weight and hemoglobin (p<0.001 for each).
Conclusion: Helicobacter pylori infection is a causative factor in growth failure in children.