Does Aerobic Exercise Training with Weight Loss Affect Serum C-Reactive Protein in Asymptomatic Obese Peri-Menopausal Women?
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- Category: Vol. 78, December 2010
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Does Aerobic Exercise Training with Weight Loss Affect Serum C-Reactive Protein in Asymptomatic Obese Peri-Menopausal Women?,DALIA M. KAMEL and SAYED A. TANTAWY
Abstract
Background: Obesity is a major problem especially in the developing countries, the excessive fat activating the pro-inflammatory process and increasing the inflammatory markers that lead to many serious diseases. In perimenopausal period women going through many hormonal changes that leads to decrease the metabolic rate.
Purpose of the Study: To investigate the effect of aerobic exercise training with weight loss on C-reactive protein (CRP).
Methodology: 50 obese perimenopausal women with body mass index (BMI) >30 kg/m2randomly assigned into 2 groups, group (A) followed a regimen of restricted diet of 1000-1200 Kcal/day. While, group (B) followed as in group (A) in addition to a program of aerobic exercise training on a treadmill 3 times/week for 40 minutes, both groups followed their program for 3 months.
Results: Showed a highly significant reduction in CRP level in both groups (p<0.001 and 0.0001) respectively and it was linear with the highly significant decrease in BMI. But when comparing CRP reduction between groups A and B there was highly significant (p<0.025) decrease in group (B) in comparison to group (A).
Conclusion: Aerobic exercise training was effective for weight loss aiming to decrease CRP which is an inflammatory marker and predictor for the incidence of cardiac diseases. So, it is very important that obese women in the perimenopausal period to reduce their weight with both diet reduction and exercise training and later on keep physically active to control body weight and guard against obesity related diseases.