Study the Effect of Three Species from Fish on Lipid Profile and Liver Function in Experimental Animals
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- Category: Vol. 80, September 2012
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Study the Effect of Three Species from Fish on Lipid Profile and Liver Function in Experimental Animals,FAHHAD ALAJMI, HANY H. MOHAMMAD, MOHAMMAD A. ALFAYEZ and BUTHAINA AL-ATHARI
Abstract
The important nutritive compound is found in fish the essential fatty acids, some of them beneficial to human health like the long chain n-3 polyunsaturated fatty acids (PUFAs). The present study was undertaken to investigate the effect of three species from fish (Zubaidi, Hamour and Saboor) on lipid profiles and liver functions in male hamsters, which fed on hyperlipidemic diet addition of 5% and 10% roasted granules fish. Total fat and fatty acids composition were analyzed. The body weight gain and daily fed intake were calculated. Lipid profiles (total cholesterol, triglyceride and HDL-c) and liver functions (ALB, AST, ALP, ALT, GGT, TBIL, TP and DBIL) were determined while LDL-c, VLDL and LDL/HDL ratio were calculated. The results revealed that feeding addition 5% of Zubaidi was the highest significant value of body weight gain compared with all groups. Diet addition of Zubaidi (5%) and (10%) and Sboor (10%) showed significant decrease for total cholesterol compared with positive control group, also triglyceride was reduction by Zubaidi 5% like negative control group. On the other side Group fed on 5%, Hamour recorded the highest value of HDL-c while LDL-c was increased significantly by group fed on 10% of Zubaidi compared with positive control. ALB increased significant by group fed 10% of Zubaidi and 5% of Hamour, while group 7 fed 5% of Saboor recorded the lowest value for ALP but increased significant by 10% Hamour. About AST, increased by positive control group and the lowest value of Hamour 5%. Results revealed reduction in ALT by group fed on 5% of Hamour, also groups fed 10% of Zubaidi and 10% of Hamour were recorded high value of TP compared with negative and positive control.