Utility of Color Doppler Ultrasonography and MRA in the Evaluation of Patients with Leg Ulcers,KHALED M. EL-GERBY, MOANES M. ENABA and MANSOUR M. MORSY
Abstract
Purpose: The aim of the study is to evaluate the role of color Doppler ultrasonography and MRA in the evaluation of the normal and abnormal vascular supply to the leg which may lead to leg ulcers.
Material and methods: Between October 2011 and May 2012, our study included fifty patients complaining from leg ulcers, they were 36 males and 14 females with age ranging from 29-75 years and mean of 52 years. Color Doppler Sonography (CDS) and Contrast Enhanced MRA (CE-MRA) examinations were done to evaluate normal and abnormal vascular supply to the leg which may lead to leg ulcers. CDS was done using combination of real time B-mode imaging system with pulsed and continuous wave Doppler facilities and the availability of color coding of signals. CE-MRA with bolus chase technique was performed for all patients.
Results: MRA study proved to be 100% sensitive, 80% specificity positive predictive of 90% and negative predictive of 50% with 90% accuracy compared to Doppler which proved to be 80% sensitive with 60% specificity, positive predictive 85.7% and negative predictive 50% with accuracy 75%.
Conclusion: The findings of this study indicate that contrast-enhanced MR angiography is highly accurate for the detection of peripheral arterial diseases which lead to leg ulcer. Contrast-enhanced MR angiography has significantly and clinically important higher sensitivity compared with duplex US and is slightly more effective for diagnosing disease because of its higher specificity.