Effect of Resisted Exercise Training on Interleukin-6 in Patients with Chronic Heart Failure
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- Category: Vol. 81, December 2013
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Effect of Resisted Exercise Training on Interleukin-6 in Patients with Chronic Heart Failure, ZEINAB M. HELMY, SHERIN H. MOHAMMED and GABER S.A. SOLIMAN
Abstract
Background and Purpose: Resisted exercise training for patients with chronic heart failure (CHF) improves exercise capacity, restores endothelial function and skeletal muscle changes. The effects of three months resisted exercise training on inflammatory cytokines (interleukin-6) in patients with CHF were studied.
Patients and Methodology: Forty male chronic heart failure patients as a result of coronary artery disease with age of 50-60 years were included in the present study. Their body mass index (BMI) >30kg/m2. They were randomly divided into two groups, each group consisted of 20 patient, the study group (group A) received a program of resisted exercise training (40-50min, resisted exercises, 3 times/week), the control group (group B) did not receive any program of exercise. Both groups received their medical treatment as prescribed by physician. The biochemical changes in inflam-matory markers (interleukin-6) were measured at the beginning of the study and after twelve weeks.
Results: Showed that a program of resisted exercise training had effect to slightly decrease Interleukin-6 but not statistically significant reduction by (0.43%) while the control group showed slightly increase by (0.28 %).
Conclusion: It was concluded that a program of resisted exercise training showed non statistically significant reduction in Interleukin-6 in chronic heart failure patients.