Pancreatic Carcinoma: Role of Multislice Tripahsic CT in Assessement of Tumor Resectability, Prospective Study,NAGAT M. KHALIFA, NOHA ABEL SHAFY, OMNIA MOKHTAR, YAHIA LABAIB and AYMAN M. ABDEL MOTTELB
Abstract
Purpose: To evaluate the role of MSCT in assessment of pancreatic tumors, its local and distant spread to determine line of treatment that should be used accordingly.
Patients and Methods: Prospective study of twenty patients (16 males and 4 females) with pancreatic masses or symptoms suggestive of pancreatic disease, their ages range from 40-66 years with mean age was 53. Multislice CT 64 detectors used, Triphasic CT liver study was performed (pre-contrast, arterial phase, porto-venous phase and delayed phase). Findings are matched with histopathological results, clinical and surgical data for operable cases.
Results: Pathology revealed pancreatic adenocarcinoma in 19 out of 20 patients. Only one case fine needle aspiration revealed inflammatory process and managed conservatively. Multislice CT was excellent in detecting unresectable tumors either because of vascular encasement seen in 17 out of 20 cases or metastatic disease.
Conclusion: MSCT is a usefull tool in detection and staging of pancreatic tumors, determination of tumor resect-ability. Further progress in preoperative staging of pancreatic ductal adenocarcinoma using multislice CT tripahsic technique should be directed toward improving early detection of small pancreatic tumors and assessment of early metastatic disease.