Salvage Mastectomy for Ipsilateral Breast Tumor Recurrence after Breast Conserving Therapy
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- Category: Vol. 81, March 2013
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Salvage Mastectomy for Ipsilateral Breast Tumor Recurrence after Breast Conserving Therapy, ABDEL HAMID H. EZZAT, ASHRAF H. IBRAHIM and REDA TABASHY
Abstract
Introduction: Ipsilateral breast tumor recurrence (IBTR) is one of the complications following breast conserving therapy that is conventionally treated with simple mastectomy. There is limited data evaluating the outcome after mastectomy for IB TR.
Patients and Methods: A retrospective review was con-ducted evaluating 176 patients operated for breast conservation during the period from January 2002 till December 2006 at the Surgical Oncology Department, National Cancer Institute, Cairo University. Thirty three patients (18.8%) experienced IBTR after breast conservation therapy (BCT). Patients with repeated lumpectomy and/or moderate disease where excluded from the study.
Resulls: The pathologic presentation was IDC (92.6%), ILC (3.4%), medullary carcinoma (3.4%) and mixed duct and lobular carcinoma (0.6%). The mean IBTR size was 5.0±0.91 cm. Mean follow-up after mastectomy was 61.03±12.23 months. Seven patients (21.2%) had post lumpectomy recur-rence (PLR) which decreased overall survival. Ninety percent of post mastectomy recurrence occurred within the first 24 months following mastectomy.
Conclusion: Mastectomy for IBTR remains an effective treatment for most patients with risk of PMR. Strict follow-up should be routine during the first 24 months.