Effects of Lifestyle Plus Exercise Intervention on Neck and Waist Circumferences in Pre-Diabetic Women
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- Category: Vol. 82, March 2014
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Effects of Lifestyle Plus Exercise Intervention on Neck and Waist Circumferences in Pre-Diabetic Women, MAGDY M. AHMED and EHAB K. ZAYED
Abstract
Aim of the Study: The aim of this study is to evaluate the effects of diet restriction and exercise training program on neck and waist circumferences in pre-diabetics.
Design: This study was conducted from October 2011 to August 2013 at October 6th University Hospital.
Patients: This study conducted on one hundred patients overweight and obese (BMI, 25-35Kg/m2) women aged 30 to 45 years for 6 months.
Intervention: The 100 women were randomly assigned to two groups. Group 1: (n=50) received weight reduction program (healthy lifestyle control, diet-induced weight loss (13 00Kcal/day) and aerobic exercise for 6 months. The exercise intervention consisted of cycle ergometer for 50 minutes, 3 times/week. Group 2: (n=50) was given general information about healthy food choices and low-caloric diet (1300kg/day) for the same period.
Main Outcomes Measures: Weight, body mass index (BMI), neck circumference (NC), waist circumference (WC), fasting blood glucose, 2 hours post-prandial blood sugar, fasting serum insulin and HOMA-IR were measured.
Results: After 6 months, women in group 1 showed a highly significant reductions in weight (p=0.001), BMI (p=0.001), neck circumference (p=0.001), Waist circumference (p=0.001), FBS (p=0.001), 2h PPBS (p=0.01), fasting serum insulin (p=0.001), and HOMA-IR (p=0.001). Women in group 2 also demonstrated significant statistically differences in the mean values of weight (p=0.001), BMI (p=0.01), neck cir-cumference (p=0.01), Waist circumference (p=0.001), FBS (p=0.001), 2h PPBS (p=0.002), fasting insulin (p=0.01), and HOMA-IR (p=0.001) after the end of the study.
Conclusions: Lifestyle modification and exercise training induced weight reduction improved all modifiable risk factors of insulin resistance and considered the best modalities in preventing type 2 diabetes mellitus in pre-diabetic individuals.