The Effect of Intraoperative Fluid Mangement on Haemodynamics during Laparoscopic Radical Cystectomy, INAS F. ABDUL AAL, MAI W. ABDALLAH, ENAS M. SAMIR and NORHAN A. ALY
Abstract
Background: Prolonged pneumoperitoneum in laparoscop-ic radical cystectomy (LRC) leads to impairement in haemo-dynamics. This is manifested by increase in systemic vascular resistance, decrease in cardiac output and arrhythmias.
Aim of the Study: To determine whether intraoperative fluid management could prevent cardiovasvular changes from hazards of pneumoperitonuem in patients undergoing laparo-scopic radical cystectomy operations.
Study Design: Randomized controlled trial.
Methodology: Eighty patients with cancer bladder sched-uled for laparoscopic radical cystectomy, classified by the American Society of Anesthesiologist (ASA) to class (ASAII or ASAIII) were divided into 2 equal groups group I received 2ml/kg/hr LR (Lactated ringer), group II received 8ml/kg/hr LR. Both groups received 8ml/kg LR as a preload.
Results: No statistical significant difference was found in HR and MAP while there was statistical significant differ-ence in CVP after 180 minutes T6 (5.6±2.42 versus 7.1±2.73).
Conclusion: In patients undergoing laparoscopic radical cystectomy, intraoperative infusion of 8ml/kg/hr Lactated Ringer could maintain haemodynamic stability without causing pulmonary edema or volume overload compared to low volume infusion of 2ml/kg/hr Lactated Ringer.