Risk Factors of Peripheral Vascular Disease in Diabetic Patients at Assiut University Hospitals
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- Category: Vol. 83, March 2015
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Risk Factors of Peripheral Vascular Disease in Diabetic Patients at Assiut University Hospitals, LOBNA F. EL TOONY, AHMAD F. THABET, LOBNA ABDEL-WAHID and MARWA M. ABO-KREASHA
Abstract
Background: Peripheral arterial disease (PAD) in diabetics is often asymptomatic as pain perception may be blunted by the presence of peripheral neuropathy. Those patients are more likely to present with an ischemic ulcer or gangrene and its screening modalities have not been uniformly agreed upon.
Objectives: To detect the baseline demographic, clinical and laboratory characteristics associated with peripheral arterial disease among diabetic patients to predict those at risk of PAD.
Patients and Methods: 200 type 2 diabetes mellitus patients attending the diabetic out-patient Clinic at Assiut University Hospital, subdivided according to their Ankle Brachial Index measurement (ABI) into 71 patients with abnormal ABI (Group I) and 129 patients with normal ABI (Group II). For all, full medical history, clinical examination, ABI by Doppler ultra-sound, in addition to ECG, RBS, HbA1C and lipid profile were done. This Study was Approved by the Ethical Committee of Assiut University.
Results: Old age, smoking, long duration of hypertension, diabetes, and ischaemic heart disease, high systolic blood pressure, high random blood sugar, elevated haemoglobin A1c and high LDL-Cholesterol were significantly higher in (Group I) than (Group II) and positively correlated with PAD. Neuropathic pain, foot ulcer, bullae or intermittent claudication pain were significantly associated with peripheral arterial disease in diabetic patients.
Conclusions: Peripheral arterial disease is a common associate with diabetes mellitus. However, the presentation could be uncommon.