The Effect of Adding Dexmedetomidine to Intrathecal Bupivacaine-Fentanyl Mixture in Knee Arthroscopy
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- Category: Vol. 84, September 2016
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The Effect of Adding Dexmedetomidine to Intrathecal Bupivacaine-Fentanyl Mixture in Knee Arthroscopy, MOHAMED ESMAT, SAAD EL-BASHA, HESHAM ABU EL-DAHAB and SAFINAZ OSMAN
Abstract
Introduction: Neuraxial anaesthesia for knee arthroscopy is a good anesthetic choice. Many drugs were added to local anesthetics as adjuvants to prolong the duration of the block. The first drugs used as adjuvants were opioids followed by clonidine. Dexmedetomidine is a newly introduced a2 agonist with favorable characteristics that may be useful in this respect.
Methods: 30 patients were included in the study devided into two groups. Group F: Received 2.5m1 hyperbaric bupivacaine 0.5% plus 25цg fentanyl and Group DF: Received 2.5m1 hyperbaric bupivacaine 05% plus 25цg fentanyl plus 5pg dexmedetotnidine. Primary outcome was the time to two segment regression in the sensory block.
Results: The time to two segment regression was significantly longer in the combined group compared to the fentanyl group. The highest sensory level and time to reach it was comparable between the two groups as well as the rate of side effecs.
Conclusion: Intrathecal dexmedetomidine as an adjuvant to the famous bupivacaine-fentanyl mixture for knee arthroscopy seems to have a favorable prolonging effect to the duration of the block with minimal side effects.