Assessment of Cardiovascular Risk Factors Pre-and Post-Bariatric Surgery, INAS T. EL-SAYED, MOHAMED D. SARHAN, MOSTAFA A. EL-SHAZLY and MAI D. SARHAN
Abstract
Background: Obesity poses serious health consequences, and bariatric surgery remains the most effective and durable treatment. The goal of this study was to identify early changes in weight parameters, blood pressure, blood glucose level and lipid profile. A trial was made to correlate these changes with the degree of weight loss.
Methods: A prospective cohort study was done including 30 obese patients (BMI 40 or 35 w th comorbidities). Demographic, clinical data, fasting and postprandial blood glucose as well as lipid profile were recorded pre-operatively as well as 2 weeks and 3 months post operatively. Results were statistically analysed and a correlation study was made between lost weight and changes in blood pressure, blood sugar and serum lipids.
Results: A statistically significant reduction of body weight parameters occurred at 2 weeks and 3 months intervals post-operatively. Both systolic and diastolic pressures improved significantly. Twenty-one patients with hyperglycemia showed rapid improvement, but post-prandial hyperglycemia returned in 12 of them 3 months later. As regards dyslipidemiawhich was present in nearly 50% of patients, lipid profile improved significantly in most of them. There was a correlation between actual total body weight loss and percent change in cholesterol, triglycerides and HDL level, as well as fasting blood sugar.
Conclusions: Bariatric surgery was followed by early significant changes in body weight parameters, improvement in blood pressure, blood sugar level and lipid profile. These changes entail a definite decrease in cardiovascular risk factors.