Comparative Study of Predictive Value of 2D Ultrasonography, Doppler of the Endometrium before and after HCG Injection on the Outcome of IVF/ICSI Cycles
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- Category: Vol. 84, December 2016
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Comparative Study of Predictive Value of 2D Ultrasonography, Doppler of the Endometrium before and after HCG Injection on the Outcome of IVF/ICSI Cycles, MOHAMED Z. ABD EL-AZIZ, HASSAN M. GAFAAR and DALIA M. AYMAN
Abstract
Objective: Is to compare the value of measuring endome-trial thickness and sub-endometrial blood flows by 2D ultrasound and Doppler to predict pregnancy during IVF/ ICSI treatment.
Study Design: 50 women candidate for IVF. Two D ultra-sound and color, Doppler of blood flow and endometrial thickness were studied on the day of HCG administration in the sub-endometrial zone and remeasured at day of embryo transfer. Patients were divided into two groups: Group A included 21 women with successful outcome (pregnancy) and Group B included 29 women with failure of pregnancy.
Results: There was no significant difference between endometrial thickness measured before and after HCG triger-ring and between pregnant and non pregnant women (p>0.5). The mean RI in patients before HCG injection was higher than that after HCG injection, the difference is statistically significant (p-value 0.025). The mean RI in no pregnancy group is higher than in pregnancy group, the difference, is statistically significant (p-value <0.01). The mean PI in patients before HCG injection was higher than that after HCG injection the difference is statistically significant (p-value 0.034).
The mean PI in no pregnancy group is higher than in pregnancy group, the difference is statistically significant (p-value 0.02). The mean S/D ratio is higher in patients before HCG injection than that after HCG injection, the difference is statistically significant (p-value 0.041).
The mean S/D ratio is lower in pregnancy group, the difference is statistically significant (p-value 0.04).
Conclusion: Assessment of sub-endometrial blood flow by 2D colour Doppler ultrasound performed before and after HCG injection in patients undergoing IVF/ICSI cycle is a good predictor of pregnancy rate.