Effect of Sleeve Gastrectomy on Lipoprotein Metabolism in Morbidly Obese Patients
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- Category: Vol. 84, December 2016
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Effect of Sleeve Gastrectomy on Lipoprotein Metabolism in Morbidly Obese Patients, AMIR K.M. ABO SAYED, AHMED H. KHALIL, NADER M. MILAD, SHERIF MOKHTAR, EMAD S. KHALLAF and MOHAMMED Sh. HATHOUT
Abstract
Background: Obesity is associated with abnormal fasting and postprandial lipids, which may link obesity with athero-sclerosis. We explored lipoprotein metabolism in morbidly obese patients treated with sleeve gastrectomy.
Methods: 20 hyperlipidemic cases were selectively choos-en and candidate for sleeve gasterectomy at Kasr Al-Aini Hospital. Blood sample was taken from them after fasting 12 hours for assessment of lipid profile {Triacylglycerols (TG), Total Cholesterol (TC), High Density Lipoprotein (HDL) and Low Density Lipoprotein (LDL) } at time of surgery, 3 months and 6 months after surgery.
Results: 20 cases of hyperlipidemia were included in the study in the period between December 2013 and January 2015 with follow-up for 6 months up to July 2015. During the study period 20 cases of sleeve gastrectomy were done at Kasr Al-Aini Hospital with marked improvement in TG, TC and HDL with less improvement in LDL.
Conclusion: Six months after sleeve gastrectomy fasting and postprandial lipoprotein metabolism is improved in morbidly obese patients.
The potential mechanisms may relate to decreased caloric intake but also to hormonal changes.