Onset and Duration of Local Anesthesia in Multiple Previous Surgeries Compared to First Time Surgery
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- Category: Vol. 84, December 2016
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Onset and Duration of Local Anesthesia in Multiple Previous Surgeries Compared to First Time Surgery, DINA M.M. ALI, MANAR M. EL-KHOLY, SAMY A. EL-SAYEH, IMAN M.A. ZAKI and ENAS M. SAMIR
Abstract
Background: Ophthalmic surgeries may be done under either regional or general anesthesia. The aim of this study is to compare local anesthetic agents, bupivacaine, levobupi-vacaine and their mixtures, to detect whether levobupivacaine has a shorter onset and a prolonged duration of anesthesia relative to its racemic isomer bupivacaine during vitreoretinal surgeries and whether there are differences in onset and duration of sensory and motor block in those who have done previous operations and those who haven’t.
Methods: One hundred and thirty six patients were enrolled in this study randomized into four groups, 34 patients each received peribulbar injection: Group I: Bupivacaine 0.5% + Hyaluronidase 30IU, Group II: Lidocaine 2% + Bupivacaine 0.5% + Hyaluronidase 30IU, Group III: Levobupivacaine 0.5% + Hyaluronidase 30IU and Group IV: Lidocaine 2% + Levobupivacaine 0.5% + Hyaluronidase 30IU.
Results: No significant difference in the duration of motor block after 180 minutes in those who have administered previous local anesthesia; between the four groups. Only in group IV, the duration of sensory block was shorter in com-parison to those who did not do previous operations (81.38 ±36.60min. versus 125.45±43 .33min) with p-value=0.01
Conclusion: Levobupivacaine 0.5% is of shorter onset of motor block, but with same onset and duration of sensory block and duration regarding motor block, compared to bupivacaine 0.5%.