The Value of Magnesium Sulfate as an Adjuvant for Ophthalmic Surgery Using Peribulbar Block, MOHAMED ABD EL-RAOUF, OSMAN M. HEFZY, AHMED A. BAWDY, MOHAMED H. ABD EL-AZIZ and NORHAN A. SHERIF
Abstract
Background: The vast majority of ophthalmic surgeries are preformed under regional anesthesia. It has become a common practice to use polypharmacy approach to enhance the onset and prolong the duration of the block.
Magnesium sulphate is a physiological calcium antagonist and competitive N-Methyl-D-Aspartate (NMDA) receptor antagonist. Studies evaluated its effect as an additive to local anesthetics in different regional techniques.
Patients and Methods: The present study involved 2 groups; each group included 20 patients undergoing elective posterior segment surgery of the eye under local anesthesia.
•Group (M25) received 25mg of magnesium sulfate in addition to the local anesthetic (2% lidocaine + 0.5% bupivacaine + hyalurindase).
•Control group (Group C) received only the local anesthetic (2% lidocaine + 0.5% bupivacaine + hyalurindase).
Conclusion: As a conclusion of this study, it was found that the addition of 25mg of magnesium sulphate is safe and effective as an adjuvant to local anesthetic mixture of bupi-vacaine and lidocaine in peribulbar eye evidenced by fastening the onset of globe block, increasing duration of akinesia and analgesia. Intraocular pressure was reduced below baseline after 15 minutes of the block.