Study of Galactorrhea in Infertile Women and its Correlation with Hypothyroidism in Egyptian Women, HAMDY
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- Category: Vol. 84, March 2016
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Study of Galactorrhea in Infertile Women and its Correlation with Hypothyroidism in Egyptian Women, HAMDY A. IBRAHIM, SAHAR ABD EL-ATTY, ODETTE W. HINDY and N. HASSAN
Abstract
Background: Female infertility refers to infertility in female humans. It affects an estimated 48 million women with the highest prevalence of infertility affecting people in South Asia Sub-Saharan Africa, North Africa/Middle East and Central/Eastern Europe and Central Asia 19% of the women had primary infertility and the others secondary infertility. The menstrual pattern was abnormal in 37.8% of infertile women with galactorrhoea.
Objectives: To estimate the three hormones Prolactin, Thyroid Stimulated Hormone (TSH) and Free Thyroxine (F-T4) in infertile females with galactorrhea and its correlation with hypothyroidism.
Methods: 72 women participated in this study in two groups:
- Group I that composed of 36 1ry infertility women com-plained with galactorrhea.
- Group II composed from 36 healthy women as a control group. Their ages ranges from 21 to 30 years. Estimation of three hormones PRL-TSH-FT4 that were analysed by chemiluminescence immunoassay (cobas) in two groups.
Results: Significant higher value of (PRL) and (TSH) (p<0.001) were observed in the patient Group (I) when com-pared with control Group II. While significant lower values (p<0.001) in F-T4 were observed in patients of Group I. When compared with control Group II.
Conclusions: There is a high incidence of hyperprolacti-naemia in 1ry infertile women mainly with galactorrhea and there is a good positive correlation between hypothyroidism and hyperprolactinemia.