The Role of MSCT in Evaluation of Thoracic Manifestations of Systemic Lupus Erythematosus
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- Category: Vol. 85, September 2017
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The Role of MSCT in Evaluation of Thoracic Manifestations of Systemic Lupus Erythematosus, YOUSSRIAH Y. SABRI, MARIAN F. FARID, SAMAR A.A. ABD EL-HAMEED and HEBATAALLAH H.M. ASSAL
Abstract
Background: Systemic Lupus Erythematosus (SLE) is a chronic, auto-immune collagen disease of unknown cause. It is 10 times more prevalent in women than in men. MSCT is the method of choice for assessment of different pulmonary abnormalities in SLE, offering the best correlation with histologic findings, disease severity, prognosis, disease pro-gression, and differential diagnosis.
Aim of the Work: The role of this study is to identify the MSCT findings in patients with thoracic manifestations of SLE, explore the role of multi-slice CT [conventional computed tomography or the HRCT], for its diagnosis and early detection of any chest involvement.
Patients and Methods: This study involved 21 patients; 17 females and 4 males, age range 14-51 years (average of 29.428 years). All patients were known cases of SLE. Cases were referred to radiology department for MSCT assessment of the chest. CT chest done to all patients using MDCT (Toshiba-Aquillion, 64 detectors). HRCT was done in 13 patients and post IV contrast done in 5 patients, CTPA was done in 3 patients.
Results: Multislice Computed Tomography (MSCT) es-pecially HRCT technique was highly dependable in detecting various CT chest signs and presentations in patients with systemic lupus erythematosis including pleural, cardiac and diaphragmatic involvement with high sensitivity in pathology detection and severity assesment.
Conclusion: We concluded that the MSCT imaging is highly capable in demonstrating the intra-thoracic manifesta-tions of SLE so it is considered essential and central, being accurate, non-invasive and of high diagnostic value.