Microalbuminuria at Mid-Pregnancy as a Predictor of Preeclampsia
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- Category: Vol. 85, September 2017
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Microalbuminuria at Mid-Pregnancy as a Predictor of Preeclampsia, MOFEED F. MOHAMED, FARID I. HASSAN, AHMED EL-LAWAH and ABDELALIM M. ABDELALIM MOSTAFA
Abstract
Objective: This study was designed to assess if a single estimation of urinary microalbumin at mid-pregnancy would be of value in the prediction of subsequent development of preeclampsia.
Study Design: This is an observational prospective (cohort) study assessing microalabuminuria at mid-pregnancy as a predictor of preeclampsia; using Radio-immunoassay random urine sample collection modality to assess for the presence of microalbumin in urine.
The study was composed of 100 women coming to the antenatal clinic for booking for antenatal care. Ninety three women who finished the study were categorized into two main groups based on the RIA urinary albumin results.
•The first group (36 women): Had microalbuminuria (30- 300 mg Alb/g Creatinine).
•The second group (57 women): Had normal levels of albumin in urine (less than 30 mg Alb/g Creatinine).
Results: In our study, differences in the age were statisti-cally significant but differences in parity and gestational age were statistically insignificant among the two groups. At booking, 38.7% of clients had microalabuminuria whereas 61.3% had normal levels of albumin in urine. There was a statistically significant difference between microabluminuria and normoalbuminuria according to mean diastolic blood pressure at delivery. Among the first group, 27.8% of cases developed preeclampsia whereas in the second group 7% of cases developed preeclampsia.
Conclusion: Microalbuminuria at mid pregnancy may be a significant predictor of pre-eclampsia.