Effect of Therapeutic Exercise Intervention on Different Complications of Stem Cell Transplantation for Patients with Severe Aplastic Anemia
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- Category: Vol. 85, March 2017
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Effect of Therapeutic Exercise Intervention on Different Complications of Stem Cell Transplantation for Patients with Severe Aplastic Anemia, MOHAMED GOUDA A. IBRAHIM, ADEL A. NOSSEIR, ZIZI M.I. ALI and MOHAMED A. SAMRA
Abstract
Background: Allogeneic Bone Marrow Transplantation (BMT) has been the treatment of choice for patients with a variety of hematological diseases, however, BMT is associated with transplant-related functional impairment, which compro-mise full rehabilitation.
Aim: The purpose of this study study was designed to determine the efficacy of therapeutic exercise on patients after stem cell transplantation.
Design: Randomized controlled clinical trial.
Subjects and Methods: Thirty patients who had severe aplastic anemia after stem cell transplantation, their ages were ranged from 18-40 years. Patients were recruited from BMT Unit at Nasser Institute Hospital, Ministry of Health. between Jan. 2016 and May 2016. They were divided randomly into 2 equal groups; Group A (study group) received exercise program in the forms of aerobic exercise, chest physiotherapy and gait training by early ambulation (30 minutes/session, three sessions/week for five weeks) in addition to routine medical care and Group B (control group) received routine medical care only and not receive any therapeutic exercise program. Patients were evaluated for their fatigue by Iowa Fatigue Scale (IFS) and Complete Blood Count test (CBC) [Hemoglobin concentration (Hb), Total Leucocyte Count (TLC) and platelets count before and after five weeks of administration of program.
Results: Independent t-test to compare post treatment test revealed that there was significant differance of IFS, Hb and platelets count between the both groups with better improvment in Group A (p<0.05).
Conclusion: The therapeutic exercise had an instantaneous effect on different complications after bone marrow transplan-tation of patients with sever aplastic anemia.