Oral Ulcers of Crohn's Disease and Oral Adverse Effects of Prescribed Medications
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- Category: Vol. 85, March 2017
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Oral Ulcers of Crohn's Disease and Oral Adverse Effects of Prescribed Medications, SHAIK M. ASIF, YAHYA A.M. AL-HUDIRY, ANAS A.M. LAHIQ, MOHAMMED A. AL-HUDIRY, MOHAMMED A. AL-SHAREEF, ABDUL-RAHMAN A.M. LAHIQ, ADEL M.A. AL-HARBAN, MAHA M. AL-QAHTANY, AMMAR Y. BAKHSH and OSSAMA A. MOSTAFA
Abstract
Objective: To identify oral manifestations and adverse effects of received medications.
Methodology: A total of 172 Crohn's disease patients aged 24-72 years were included in this study (84 females and 88 males). A self-administered questionnaire was constructed by researchers with open and closed-ended questions related to oral manifestations, duration and frequency of prescribed medications and adverse effects of mediations.
Results: Almost two thirds of patients (65.7%) experienced oral ulcers and 24.4% suffered from recurrent oral ulcers (1- 3 times in a month). Most of patients (88.4%) used to take their prescribed medications every day, 50.6% used to go for oral health check-up once every three months, while 5.8% never went for check-up for oral health. Pain due to oral ulcers was very severe in nature among 11.5%. Difficulty in masti-cation was experienced by 65.6% of the patients. Nevertheless, 85.8% did not receive medications for their oral ulcers, 6.2% received intra-lesional corticosteroid injections while 7.1% used topical anesthetics. Most patients (76.1%) felt relieved after receiving treatment, while 38.1% had foul taste and 18.6% had bleeding gingiva.
Conclusions: Oral ulcerations are common among Crohn's disease patients. It is important that Crohn's disease patients undergo frequent preventive oral care to avoid oral infections and hard and soft tissue destruction.