Role of Diffusion Weighted Magnetic Resonance Imaging in Assessment of Breast Lesions
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- Category: Vol. 85, June 2017
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Role of Diffusion Weighted Magnetic Resonance Imaging in Assessment of Breast Lesions, AMR M.T. EL-BADRY, RABAB M. ABO SOBAA and MOHAMED A. ZIDAN
Abstract
Background: Magnetic resonance is a tool for diagnosis of breast tumor and its use is rapidly increasing. However, an overlap between benign and malignant still exist. For this reason advances in MRI have shown the potential in bridging the gap between sensitivity and specificity, among this tech-nique diffusion weighted MRI (DWI).
Objective: The aim of this study is to demonstrate the value of diffusion weighted magnetic resonance imaging in differentiation of benign from malignant breast lesions as diffusion weighted imaging has the potential to improve specificity and heighten sensitivity and thereby improve diagnostic accuracy.
Material and Methods: Diffusion weighted MRI studies on 40 female patients with suspected breast lesions by mam-mography and ultrasound were evaluated. Routine T1 weighted and T2 fat suppressed STIR sequences were performed. Diffusion weighted imaging of the entire breast was performed. The ADC maps of each lesion were done using 3 different p-values (0, 800, 1500). The mean ADC values were correlated with histopathological diagnosis.
Results: Of these forty cases, twenty cases showed re-stricted diffusion and twenty cases had facilitated diffusion which ware confirmed by histopathological findings. Thirteen cases were invasive ductal carcinoma, six cases were invasive lobular carcinoma, four cases were fibroadenoma, two cases were granulomatous mastitis, two cases were phylliod tumor, one case was medullary carcinoma, one case was fibroadenosis and eleven cases were negative for malignancy.
Conclusion: Diffusion weighted imaging is a potential resource as a coadjutant of MRI in differentiation of benign from malignant breast lesions. The use of diffusion weighted imaging in standard breast MR imaging protocol improves specificity and heighten sensitivity and thereby improves the diagnostic accuracy leading to decrease the number of unnec-essary breast biopsies. DWI should be included as a routine modality when examining any breast lesion by MRI.