Intravascular Ultrasound-Guided Management of Angiographically Intermediate Non-Culprit Coronary Artery Lesions in Acute Coronary Syndrome, FAROUK M. FARES, AKRAM M. ABD ELBARY, AHMED H. MOWAF, MOHAMED A. SHAWKY and HELMY H. ELGHAWABY
Abstract
Background: The assessment of intermediate coronary lesions using coronary angiography is often challenging. The purpose of this study was to use an intravascular ultrasound-guided strategy to determine the anatomical significance of angiographically intermediate non-culprit coronary lesions to help in their management in the setting of ACS.
Methods: We conducted an intravascular ultrasound studies on sixty one angiographically intermediate non-culprit coronary lesions in twenty eight patients with Non ST elevation ACS. Revascularization was recommended when percent area steno-sis 70%
Results: Minimal and maximal lumen diameters were significantly lower (p<0.001), MLA was significantly lower (p<0.001) and percent area stenosis was significantly higher in revascularization group (p<0.001). MLA & plaque burden are the main predictors for lesion anatomical significance with (p<0.001, OR=0.25, 95% CI=0.12-0.55) and (p=0.011, OR=2.0, 95% CI=1.2-3.3) respectively.
Conclusions: MLA & plaque burden are the main predic-tors for lesion anatomical significance.