A Comparative Study for the Effect of Pressure-Controlled versus Volume-Controlled Ventilation during One-Lung Ventilation on Oxygenation
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- Category: Vol. 85, June 2017
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A Comparative Study for the Effect of Pressure-Controlled versus Volume-Controlled Ventilation during One-Lung Ventilation on Oxygenation, RAMADAN M. ABD EL-MOTAGALLY, HOSSAM SALAH EL-DIN, HISHAM ABD EL-WAHAB, YASSER MOHAMMED and HEBA NABIL
Abstract
Background: Many thoracic surgeries require one-lung ventilation in order to be completed however it can induce hypoxemia, lung injury, and release of inflammatory mediators by different mechanisms. Pressure-Controlled Ventilation (PCV) has gained interest due to its potential advantages over Volume-Controlled Ventilation (VCV).
Aim: The aim of this study was to compare between the effect of the two different modes of mechanical ventilation on oxygenation.
Material and Methods: We started mechanical ventilation of 50 patients underwent thoracic surgery in the lateral decu-bitus position with initial two-lung ventilation with VCV, then patients were randomly divided into two groups; in the first group OLV was achieved with PCV (inspiratory pressure to provide a tidal volume of 6mL/kg), and in the second group OLV was achieved with VCV (tidal volume 6mL/kg). Hemo-dynamic parameters and Arterial Blood Gases (ABG) were measured at different times throughout the procedure.
Results: There were no significant differences in the measured parameters between both groups during OLV, apart from SaO2 that was significantly lower in VCV group. PaCO2 measurements were significantly increased during OLV in both groups.
Conclusion: SaO2 was significantly higher in PCV group compared to VCV group during OLV.