Safety of Low Dose Atracurium Added to Lidocaine, Bupivacaine and Hyaluronidase Mixture in Percaruncular Peribulbar Anesthesia for High Myopes Undergoing Phacoemulsification (A Randomized Controlled Trial)
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- Category: Vol. 86, March 2018
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Safety of Low Dose Atracurium Added to Lidocaine, Bupivacaine and Hyaluronidase Mixture in Percaruncular Peribulbar Anesthesia for High Myopes Undergoing Phacoemulsification (A Randomized Controlled Trial), MAHA M.A. MOSTAFA, NAZMY E. SEIF, MAHA M.I. YOUSSE, MAHMOUD M. SOLIMAN and ASHRAF M. AMIN
Abstract
Background: The current study explored the safety of adding low dose atracurium to lidocaine, bupivacaine and hyaluronidase mixture in percaruncular peribulbar anesthesia for high myopes undergoing phacoemulsification.
Methods: 82 ASA-PS I-III patients scheduled for phacoe-mulsification with high myopia were enrolled in this rand-omized controlled double-blinded trial. The enrolled patients were randomly allocated to one of two groups. Group C (n=41) received 2.5ml of lidocaine 2%, 2.5ml of bupivacaine 0.5% with hyaluronidase 15IU/ml and 1ml normal saline, while patients in Group A (n=41) received the same mixture with 5mg atracurium. Patients' hemodynamics, peripheral O2 saturation, occurrence of intraoperative pain and incidence of were recorded.
Results: There were no major complications in any of the 82 cases. The incidence of minor complications between both groups were comparative. Chemosis occurred in 12.2% of Group A and in 24.3% of Group C. Sub-conjunctival hemor-rhage occurred in 4.9% of patients of both groups. Local hyperemia were only observed in Group A (7.3%) with no statistical significance.
Conclusion: Adding 5mg atracurium to LA solution did not increase the incidence of complications in percaruncular block in high myopes.