Association of Helicobacter Pylori Infection with Portal Hypertensive Gastropathy in Liver Cirrhosis
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- Category: Vol. 86, June 2018
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Association of Helicobacter Pylori Infection with Portal Hypertensive Gastropathy in Liver Cirrhosis, AFAF T. EL-NASHAR, HASSAN A. HASSANIEN, ASHRAF A. ASKER and HANAA M. ABD EL-AZEEM
Abstract
Background: Portal hypertensive gastropathy (PHG) is an important cause of morbidity in patients with Liver cirrhosis (LC). Helicobacter pylori (HP) infection is a common cause of gastritis and is an endemic disease in Egypt.
Aim of the Work: To study the presence of H. pylori infection in cases of LC with and without PHG.
Material and Methods: Fifty patients with LC including 25 cases with PHG and 25 cases without PHG who attended Sohag Faculty Hospital during the period 9/2016-3/2017 were examined for the presence of H pylori infection histologically using Hematoxyline and Eosin and Geimsa stains. The corre-lation between H pylori infection and the severity of PHG was studied statistically.
Results: H. pylori were detected in 76% of cases of LC (72% in LC with PHG and 80% of cases LC without PHG). Although there was an association between H pylori infection and the severity of PHG (5/7 cases), there was no statistically significant difference between H pylori infection and PHG.
Conclusion: H. pylori infection can be seen in cases of LC irrespective of the presence or absence of PHG more than in general population.