Impact of Variable Types of Preconditioning Upon Inotropic Score in Adult Patients Undergoing Cardiac Valve Replacement Surgery: A Randomized Clinical Trial, MAHMOUD ABD EL-AZEZ, EMAD Z. KAMEL, MOHAMED MAHMOUD and SALMA I. AHMED
Abstract
Background: The objective of this study was to validate the impact of cardiac preconditioning (ischemic versus phar-macological) upon postoperative inotropic score in adult patient undergoing open heart surgery.
Aim of Work: Is to validate the impact of Sevoflurane versus ischemic & Sevoflurane pc upon postoperative inotropic score in adult patient undergoing open heart surgery.
Material and Methods: Thirty ASA II-IIIadult undergoing open heart surgery wereincluded in the study. They were randomly allocated into2 groups, Group A (15 patients). Anaesthetized by Sevoflurane as a pharmacologic precondi-tioner, Group B (15 patient) ischemic preconditioning was done after induction and before cardiopulmonary bypass by inflation the cuff of blood pressure above 200mmhg in the lower limb every 5min for 3 cycles.
Results: Non significant difference between the two groups regarding to the inptropic score and icu stay.
Conclusion: Both ischemic and pharmacological cardiac preconditioning could offer some sort of cardiac protection reflected upon inotropic score.