Assessment of Efficiency of Using Clinical Pulmonary Infection Score (CPIS) on the Outcome and Cost of Mechanically Ventilated Cases
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- Category: Vol. 87, June 2019
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Assessment of Efficiency of Using Clinical Pulmonary Infection Score (CPIS) on the Outcome and Cost of Mechanically Ventilated Cases, SARA A.A.M. HEIKAL, SALWA ABD EL-AZEEM, SAHAR YASSIN, DOA'A A.E. SALEH and LAMIA'A H. MOHAMMED
Abstract
Background: Ventilator-Associated Pneumonia (VAP) is a common Healthcare Associated Infection (HAI) in critical care department; VAP occurs frequently and is associated with significant morbidity and mortality in critically ill patients.
Aim of Study: To improve health outcome of patients on Mechanical Ventilation (MV) through early diagnosis of (VAP), early management with appropriate antibiotics pre-scription using Clinical Pulmonary Infection Score (CPIS) and measurement the cost of hospital stay and cost of the antimicrobial therapy.
Methods: Operational research, quasi-experimental inter-ventional study design. The study was conducted in the in Critical Care Department in the Faculty of Medicine Cairo-University. The study has 2 phases Phase 1: Recruiting the Control group (40 cases) on MV not using CPIS. Phase 2: recruiting the Interventional group (40 cases) on MV using CPIS.
Results: The CPIS was lower in intervention group at the day 3 with significant difference p=0.01. Deaths in intervention group (who were followed by CPIS) were insignificantly lower. The median of total cost and medication cost were lower in intervention group and the median of antibiotic cost was significantly lower in patients (who were followed by CPIS) in intervention group than control group p=0.01.
Conclusion: CPIS considered tool to monitor patient's condition on MV and monitor their response to antibiotic treatment for early modification which in turn reflected on hospital stay and cost.