Clinical Audit on Management of Central Nervous System Infections, ELSAYED K. ABD EL-KARIM, DUAA M. RAAFAT and SAFAA M. ABD EL-ALEEM
Abstract
Background: Central Nervous System (CNS) infections cause significant mortality and neurological morbidity through-out the world children.
Patients and Methods: All patients aged beyond neonates admitted to Assiut University Children Hospital (during six month duration) from 1/6/2017 to 30/11/2017 with any symp-toms or signs of meningitis, encephalitis or meningeoencepha-litis including fever, convulsions, disturbed conscious level were included in this study to assess how much adopted protocols in management of CNS infections are applied.
Results: Shows that 100% of patients had lumber puncture, CSF culture was done to 16.4% of all cases, the first choice of empirical treatment were Ampicillin plus cefotaxime in about 82% of all cases, vancomycin came after in 19.7% of them, then ceftriaxone in 18%, nearly all patients were treated with steroid except for one case, 88.5% were treated with antiviral, mainly all Children <3 month with unconfirmed disease treated with cefotaxime + ampicillin for 14 day except for 25% of them, only 29.8% of Children >3 month with unconfirmed disease treated with ceftriaxone for 10 days.
Conclusion: We need to stick with the international guidelines as a reference standard to avoid miss diagnosis and complications of CNS infections to improve the health services provided in Neurology Unit.