The Value of Non-Alcoholic Fatty Liver Diseases Detected by Fibroscan in the Prediction of Coronary Heart Diseases Detected by Multi-Slice CT Angiography
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- Category: Vol. 87, December 2019
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The Value of Non-Alcoholic Fatty Liver Diseases Detected by Fibroscan in the Prediction of Coronary Heart Diseases Detected by Multi-Slice CT Angiography, NERMIN M. NAGA, MANAL F. HAMISA, SAMIA M. SHARAF ELDEEN and RASHA L. YOUNIS
Abstract
Background: Non-alcoholic hepatic steatosis, considered to be the hepatic manifestation of Metabolic Syndrome (MS), is the commonest liver disease in industrialized countries and it is associated with increased incidence for Coronary Artery Disease (CAD).
A high percentage of hepatic steatosis was detected in patients who examined by invasive coronary angiography with increased incidence of relevant coronary artery disease in patients with fatty liverin comparison to those who did not have signs of lipid accumulation in liver on ultrasound.
Aim of Study: This study aims to assess the frequency of non-alcoholic fatty liver diseases in coronary heart disease patients by using a new diagnostic tool: TE (Fibroscan) and coronary CT angiography.
Patient and Methods: A total number of 60 patients suffered from Non-Alcoholic Fatty Liver Disease (NAFLD) to be examined by fibroscan examination with CAP parameter and then computed tomography coronaries angiography by using agaston score.
Results: The age of the patients ranged from (32-72) years with mean age of 52 years, 34 male patients (56.7%) and 26 female patients (43.3%), in this study there were 28 patients suffered from hypertension, 28 patients suffered from DM, 20 patients were smokers, 18 patients were obese and 6 patients had no risk factors with overlap of the risk factors. In this study there were 18 patients did not suffer from coronary stenosis, 10 patients suffered from minimal stenosis, 6 patients suffered from mild stenosis, 16 patients suffered from moderate stenosis and 10 patients suffered from severe stenosis according to Agaston score. According to CAP parameter in this study there were 12 patients suffered from mild steatosis, 16 patients suffered from moderate steatosis, 28 patients suffered from severe steatosis and 4 patients did not suffered from steatosis.
Conclusions: The fibroscan is the best non-invasive technique in diagnosis of the hepatic steatosis. The multi-detector CT coronary angiography is a good method in diag-nosis of the coronaries diseases and stenosis provide excellent diagnostic results. Nonalcoholic hepatic steatosis that deter-mined by fibroscan, is strongly correlated with coronary artery atherosclerosis therefore, be a relevant predictor of coronary-diseases.