Correlation between Left Ventricular Diastolic Dysfunction and Dyslipidemia in Symptomless Patients with Newly Diagnosed Diabetes Mellitus-II
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- Category: Vol. 89, December 2021
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Correlation between Left Ventricular Diastolic Dysfunction and Dyslipidemia in Symptomless Patients with Newly Diagnosed Diabetes Mellitus-II, HESHAM EL SAYED LASHIN, ABULFETOUH EID ALENANY and MUSTAFA MOHAMED ELSANDAROSY
Abstract
Background: The frequency of heart failure (HF) in cases with Diabetes mellitus (DM) is elevated even in the nonat-tendance of hypertension (HTN) and coronary artery disorder (CAD). Aim of Study: This study aims to investigate the prevalence of left-ventricular (LV) systolic and diastolic dysfunctions (DD) in symptom less cases with newly diagnosed DM-II, and assess the association among LVDD and dyslipidemia in those cases. Subjects and Methods: This was a cross-sectional research involving cases with a new detected (within 1-yr) DM-II; all cases were aging from 30 to 60-yrs, normo-tensive and clin-ically symptomless and visited the out-patient clinics of the endocrinology unit at Mustasharak Hospital from January 2020 to the end of June 2021, Demographic parameters, risk-factors and waist-hip ratio (WHR) were evaluated. Blood specimens for lab analyzing were collected. Comprehensive echo-cardiography has been done to assess systolic and diastolic functions (DF). Results: LA size and volume index, de-acceleration time and E/e’ were highly significant in DM-cases with HbA1c >!7.5 in comparison to diabetics with normal HbA1c. Mean-while, E wave, E/A ratio and Isovolumetric relaxations time were low significantly in DM-cases with HbA1c >!7.5. More-over, there was a highly significance change among the study groups in regard to diastolic function grades. Conclusion: Diastolic dysfunction (DD) has a high prev-alence in a newly detected DM-cases and looks to be associated positively with the HbA1c-levels, dyslipidaemia, obesity, and the DM period.