Comparison of Amniotic Membrane Transplantation Versus Autologus Stem Cell Transplantationfor Recurrent Pterygium
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- Category: Vol. 77, June 2009
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Comparison of Amniotic Membrane Transplantation Versus Autologus Stem Cell Transplantationfor Recurrent Pterygium,YASSER KHALIFA, OSAMA AL-NAHRAWY, EHAB GHONEIM and AHMAD ANWAR
Abstract
Purpose: To compare the outcome of amniotic membrane transplantation (AMT) versus autologus limbal stem cell trans-plantation (LSCT) in the management of recurrent pterygium.
Setting: Suez Canal University Hospital, Ophthalmology Department, Ismailia, Egypt.
Methods: This is a comparative prospective case series study included forty two eyes with recurrent pterygia. They were equally and randomly assigned to either amniotic mem-brane transplantation (AMT) or autologus limbal stem cell transplantation (LSCT). Eyes were analyzed preoperatively and followed for 6 months postoperatively.
Results: The study included 18 males and 24 females. The mean age was 51.09±11.3 years in the AMT group and 43.57±14.9 in the LSCT group.
The mean preoperative best corrected visual acuity was 0.41±0.29 in the AMT and 0.52±0.22 in the LSCT groups upon inclusion into the study. The mean postoperative best corrected visual acuity was 0.68±0.21 in the AMT and 0.79± 0.18 in the LSCT groups. There was a highly statistically significant difference between the results.
There were no intraoperative complications. While post-operatively complications including vascularization, cicatri-zation, chronic inflammation and recurrence were higher in the AMT group.
Conclusion: The data support the efficacy of autologus limbal stem cell transplantation for recurrent pterygium with favorable outcome and less complication.