Retrospective Study of Anophthalmia/Microphthalmia Cases
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- Category: Vol. 78, June 2010
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Retrospective Study of Anophthalmia/Microphthalmia Cases,KARIMA L. SHALABY and MOSTAFA BAHGAT
Abstract
Purpose of the Study: To evaluate morphologic data, risk factors, associated ocular as well as systemic abnormalities in cases of anophthalmia and microphthalmia.
Design: Retrospective, descriptive study.
Case Report: Four cases of anophthalmia were seen in Pediatric Clinic, Tripoli Eye Hospital in the first quarter of 2007. Two cases were boys and two were girls. Two cases had bilateral anophthalmos. The other two cases had one anophthalmic eye and the second eye was microphthalmic. So, we had 6 eyes with anophthalmia and 2 eyes of mi-crophthalmia. Microphthalmic eyes showed chorioretinal colobomata and optic coloboma with no fixation. History of consanguinity was positive in one case. No other ocular or systemic abnormality were detected. All four cases came from western part of Libya, Aljabel Algarbi. One case gave history of folic acid intake by the mother during pregnancy, another case gave history of mother fever during pregnancy.
Recommendations: Proper antenatal care, avoid old age pregnancy, minimize multiple pregnancies, avoid environmen-tal factors that may cause anophthalmia, microphthalmia. Proper genetic counseling is also needed. Antenatal diagnosis of these anomalies through chromosome analysis, U/S and MRI examinations. We also recommend proper management of these cases to improve vision, cosmetic appearance and avoid psychological disorders.