The Integral Role of Metabolic and Perfusion Imaging in Assessment of Myocardial Scar: Comparison between 18F-FDG PET and 99Tc-Sestamibi
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- Category: Vol. 82, June 2014
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The Integral Role of Metabolic and Perfusion Imaging in Assessment of Myocardial Scar: Comparison between 18F-FDG PET and 99Tc-Sestamibi, MAGED ABD EL-GALIL HAMED
Abstract
The Purpose: Viable myocardium has the potential to re-cover in function after intervention, whereas scarred tissue will not recover even after revascularization. Nuclear imaging tech-niques using either PET or SPECT have played a major role in this field. In this study, myocardium viability assessed by 99Tc MIBI, and 18 F-FDG, with identification of scar by each imag-ing modality.
Methods: Comparative cross section study, 31 patients were included in our study and all were assessed by TC-99m MIBI myocardium scan and F1 8 FDG myocardial scan.
Results: By using paired t sample test to detect the presence of difference in assessment of the scarred segments between TC 99 MIBI scan and FDG PET there was statistically differ-ence between both of them.
Conclusion: Perfusion imaging by Tc 99m MIBI alone is not a ideal method to define myocardial viability compared to metabolic imaging by F18 FDG. So the combined imaging by Tc-99m MIBI myocardial perfusion SPECT and 18 F-FDG myocardial metabolic PET should be used widely in clinical
practice.