The Role of Intensive Phototherapy Device in Treatment of Neonatal Jaundice,
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- Category: Vol. 84, June 2016
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The Role of Intensive Phototherapy Device in Treatment of Neonatal Jaundice, OSAMA A. ELFEKY, AMR M. EL-KHASHAB, AHMAD A. SOBEIH and MOHAMMED G. ABD EL-HAMEED
Abstract
Objectives: To assess the effectiveness of intensive pho-totherapy in treatment of neonatal jaundice and elimination of exchange transfusion.
Methods: The case control study was conducted at El-Galaa Teaching Hospital, from October 2014 to April 2015, and comprised 200 newborns with indirect hyperbilirubi-naemia. The 100 subjects were treated with Bilisphere 360 (Bilisphere group) compared with 100 who had been treated with conventional phototherapy (control group). Both groups were subjected to complete clinical evaluation and laboratory investigations.
Results: Bilisphere 360 decreased the need for exchange transfusion to 16 (16.0%) neonates of the Bilisphere group versus 66 (66.0%) of the control group (p<0.001); decreased the level of serum bilirubin as exchange transfusion [5.7mg/dl (22.5%) in the subjects vs. 6.0mg/dl (22.8%) in the controls]; shortened the duration of phototherapy (1.7 days in the subjects, vs. 4.1 days in the controls; p<0.001).
Conclusion: The use of intensive phototherapy (Bilisphere 360) in the treatment of indirect pathological hyperbilirubi-naemia is very effective in lowering total serum Bilirubin when its level is within 2-3mg/dl (34-5umol/l) of the exchange transfusion level. Bilisphere 360 has succeeded in reducing exchange transfusion and duration of phototherapy.