Role of Laparoscopy in Management of Hepatocellular Carcinoma
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- Category: Vol. 84, September 2016
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Role of Laparoscopy in Management of Hepatocellular Carcinoma, AHMED SHEHTA, THARWAT KANDIL, GAMAL EL-EBIDY, WALEED ASKAR and HO-SEONG HAN
Abstract
HepatocelIular Carcinoma (НС( is the fifth most common cancer in the world. Liver Resection (LR) is a widely accepted as a potentially curative treatment. Laparoscopic surgery for liver procedures has been slow to develop. Initially introduced for staging procedures, it has now been implemented for uncomplicated LRs in НСС. It remains unclear whether laparoscopic surgery is of benefit to patient outcomes following LR for НСС.
Patients and Methods: We retrospectively reviewed the data for all patients who underwent laparoscopic liver surgery for НСС at Seoul National University Bundang Hospital, Korea during the period between July 2004 and July 2014.
Results: During the study period 274 cases underwent different laparoscopic liver procedures for НСС. 231 cases underwent Laparoscopic Liver Resection (LLR), 19 cases underwent combined LLR and Laparoscopic Radiofrequency Ablation (LRFA), and 24 cases underwent laparoscopic RFA alone for НСС.
In LLR group, 40 cases (16%) had postoperative morbidity, and 2 cases (0.8%) had early postoperative mortality. The 1, 3,5 years Overall Survival (OS) rates were 93.4%, 87.3%, 81.8% respectively. The 1, 3, 5 years Disease Free Survival (DFS) rates were 72.8%, 51.3%, 43.8% respectively.
In LRFA, the 1, 3, 5 years OS rates were 100%, 93.5%, 87.7% respectively. The 1, 3, 5 years DFS rates were 56.8%, 27.4%. 27.4% respectively.
Conclusion: Laparoscopic liver surgery is safe and feasible for the management of НСС in experienced hands.