Endoscopic Ultrasound Guided Celiac Plexus Neurolysis (EUS-CPN) in Patients with Cancer Pancreas
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- Category: Vol. 85, December 2017
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Endoscopic Ultrasound Guided Celiac Plexus Neurolysis (EUS-CPN) in Patients with Cancer Pancreas, ENAS A.R. AL-KAREEMY, WAEL A. ABBAS, ZAIN SAYED, AHMED M. ASHMAWY, MOHAMED A.A. ABO-ZAID and AL-SHIMAA H.B. ABO-TALEB
Abstract
lnsroduction: With rising burden of pancreatic cancer that is usually discovered late in Egyptian population, the need to control cancer-related pain is deemed to be a crucial issue. It is well known that pancreatic cancer pain is commonly encountered with intolerabIe pain that is difficult to control. The presence of pain on initial diagnosis not only impacts the quality of life, but also predicts the prognosis of the disease. With the advent of selective celiac plexus neurolysis, the transmission of pain sensation to the pancreas is selectively inhibited and the potential systematic side effects of narcotics are reduced.
Material and Methods: This study has been conducted in Assiut University Hospitals from June 2015 to June 2016 and was cashed out on 20 patients suffering from severe abdominal pain (according to NRS) due to cancer pancreas, who were subjected to endoscopic ultrasound guided celiac plexus neurolysis.
Results: Endoscopic ultrasound guided CPN was effective in alleviation of pain by 73.9%, improving patients sleep rhythm by 68.9% and as regard psychological aspect; also EUS-guided CPN was effective in improving patients psychological aspect by 61.4% in comparison to pre-procedure scores. In the current study we approved the safety of BUS-guided CPN without any reported complications in all cases that have been concluded in the study.
Conclusion: Celiac plexus neurolysis is a technique that can potentially improve pain in pancreatic cancer. EUS-guided CPN is a safe and effective technique in pain alleviation and improving patients' quality of life.