The Effect of Adding Dexmedetomidine to Levobupivacaine in Scalp Nerves Block on Intra and Postoperative Hemodynamics in Supratentorial Craniotomy Operations
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- Category: Vol. 85, March 2017
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The Effect of Adding Dexmedetomidine to Levobupivacaine in Scalp Nerves Block on Intra and Postoperative Hemodynamics in Supratentorial Craniotomy Operations, MAHMOUD ABD EL-AZIZ, NEMAAT IBRAHIM, NEVAN MEKAWEY, NADER NOSHEY and MOHAMED FARID
Abstract
Background: We compared in this study the benefits of adding the new a2 adrenergic blocker dexmedetomidine to levobupivacaine in SNB for patients undergoing craniotomy for supratentorial tumors as regarding effect on hemodynamics intra and post operative.
Patients and Methods: In the study 60 patients randomly divided in 2 equal groups, one received SNB with only levobupivacaine L, and the other group received SNB with levobupivacaine plus dexmedetomidine LD. Hemodynamic (mean arterial blood pressure and heart rate) was recorded at baseline, 5 minutes after skin incision, 5 minutes after dural incision, 5 minutes after dural closure, 5 minutes after extu-bation and at 4, 8,16, 24 hours post extubation.
Results: Patients in group LD had significantly lower HR and MAP during intra and postoperatively.
Conclusion: We found that addition of dexmedetomidine to levobupivacaine in scalp nerve block gives better control of hemodynamic measurements and prevent hypertention and tachycardia intra and postoperatively.