Vol. 85, March 2017

The Effect of Adding Dexmedetomidine to Levobupivacaine in Scalp Nerves Block on Duration of Analgesia Postoperatively in Supratentorial Craniotomy Operations

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The Effect of Adding Dexmedetomidine to Levobupivacaine in Scalp Nerves Block on Duration of Analgesia Postoperatively in Supratentorial Craniotomy Operations, MAHMOUD ABD EL-AZIZ, NEMAAT IBRAHIM, NEVAN MEKAWEY, NADER NOSHEY and MOHAMED FARID

 

Abstract
Background: In this study we compared the benefits of adding the new a2 adrenergic blocker dexmedetomidine to levobupivacaine in SNB for patients undergoing craniotomy for supratentorial tumors as regarding effect on duration of postoperative analgesia post operative heart rate and mean arterial blood pressure.
Patients and Methods: 60 patients were enrolled in the study randomly divided in 2 equal groups, one received SNB with levobupivacaine L, and the other group received SNB with levobupivacaine plus dexmedetomidine LD. Postoperative pain assessment was done after 5 minutes 4 hours, 8 hours, 16 hours and 24 hours of extubation. In the postoperative ICU using Visual Analogue Scale (VAS). Heart rate and mean arterial blood pressure has been recorded at 5 minute after extubationn and at 4, 8,16, 24 hours post extubation.
Results: Patients in Group LD had significantly lower HR and MAP and longer duration in analgesia than Group L in postoperative period.
Conclusion: We found that addition of dexmedetomidine to levobupivacaine in scalp nerve block increase duration of analgesia and gives better control of hemodynamic measure-ments postoperatively.

 

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