Comparison of Intrathecal Magnesium and Fentanyl as Adjuvants to Levobupivacaine in Parturients Undergoing Elective Cesarean Sections
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- Category: Vol. 85, March 2017
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Comparison of Intrathecal Magnesium and Fentanyl as Adjuvants to Levobupivacaine in Parturients Undergoing Elective Cesarean Sections, MOHAMED H. KAMAL, JEHAN H. IBRAHIM, ABEER A. SAAED, MARWA S. ZAYED and MARIANNE M. YOUSSEF
Abstract
Background: Spinal anesthesia is the most commonly used regional technique for cesarean section. The addition of various additives may allow the dose of local anesthetic to be reduced, producing a synergistic effect. The aim of this study was to investigate the block characteristics of using different additives to intrathecal levobupivacaine.
Methods: After approval of College Ethical Committee, 50 parturient with American Society of Anesthesiologists I-II undergoing elective cesarean section were enrolled for study with their informed consent. They were randomly divided equally to two Groups each parturient received intrathecal 2.5ml in form of 2ml 0.5% levopubivacaine completed to 2.5ml as follow: With 0.5ml fentanyl (25μg) Fentanyl group (group-F) and with 0.5ml 10% MgSo4 (50mg) Magnesium sulphate group (group-M).
Results: Spinal anesthesia is the most commonly used regional technique for cesarean section. The addition of various additives may allow the dose of local anesthetic to be reduced, producing a synergistic effect that is more prolonged in levobupivacaine and fentanyl group as compared to levobupi-vacaine and magnesium group.
Conclusion: Both regimen were effective in providing surgical anesthesia and hemodynamic stability, but levobupi-vacaine + fentanyl group offered an advantage of rapid onset of sensory and motor block and prolonged duration of sensory block and postoperative analgesia.