Comparison of Intrathecal Dexmedetomidine and Fentanyl as Adjuvants to Levobupivacaine in Parturients Undergoing Elective Cesarean Sections, MOHAMED H. KAMAL, JEHAN H. IBRAHIM, ABEER A. SAAED, MARWA S. ZAYED and MARIANNE MAGDY
Abstract
Background: The aim of this study was to evaluate the onset, duration of sensory and motor block, duration and quality of post-operative analgesia, and adverse effects of dexmedetomidine or fentanyl given intrathecally levobupi-vacaine in patients undergoing elective caesarean sections.
Methods: After approval of College Ethical Committee, 50 parturient with American Society of Anesthesiologists I-II undergoing elective cesarean section were enrolled for study with their informed consent. They were divided to two Groups each parturient received intrathecal levopubivacaine plus fentanyl or dexmedetomidine.
Results: Spinal anesthesia is the most commonly used regional technique for cesarean section. The addition of various additives may allow the dose of local anesthetic to be reduced.
Conclusion: Both regimen were effective in providing surgical anesthesia and hemodynamic stability, but levobupi-vacaine + fentanyl group offered an advantage of rapid onset of sensory and motor block and prolonged duration of sensory block and post-operative analgesia.