The Role of the Pharmaceutical Industry in Sustainability Initiatives: (Review Artical)
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- Category: Vol. 85, March 2017
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The Role of the Pharmaceutical Industry in Sustainability Initiatives: (Review Artical)
Abstract
Background: The pharmaceutical industry has increas-ingly focused on nanomedicine and nanoparticle-based drug delivery to improve treatment efficacy and reduce side effects. However, the production of these nanomaterials often involves hazardous substances, raising concerns about their environ-mental impact. Green chemistry principles offer an opportuni-ty to develop more sustainable nanopharmaceutical manufac-turing processes. Aim: This review examines the use of green chemistry con-cepts to enhance the production and modification of nanodrug delivery systems. It introduces the term “green nanomedicine” and provides a detailed account of eco-friendly manufacturing approaches for various nanoparticle-based drug carriers. Methods: The review surveyed the literature on green chemistry applications in the development of nanoparticles, polymer nanoparticles, and protein/lipid-based drug delivery vehicles. A concise overview of ongoing green manufacturing techniques is presented. Results: Green chemistry has been increasingly employed to synthesize metal nanoparticles, such as iron oxide and mag-nesium nanoparticles, which have shown therapeutic potential with reduced toxicity. Natural polymers and biomass-derived compounds have also been utilized to fabricate more sustaina-ble nanoparticle carriers. Conclusion: The adoption of green chemistry principles in nanomedicine can lead to the development of safer and more environmentally friendly nanopharmaceuticals. Future research should focus on expanding the application of green chemistry across the entire lifecycle of nanomedicine, from synthesis to disposal, to ensure the broad implementation of sustainable practices in the pharmaceutical industry