Speckle Tracking Echocardiography in Diabetic Patients with STEMI
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- Category: Vol. 84, December 2016
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Speckle Tracking Echocardiography in Diabetic Patients with STEMI, AMIRA M. ISMAIL, WAEL SAMY, RANDA ALY, SUZY FAWZY and KHALED HUSSEIN
Abstract
Background: Noninvasive assessment of MI based on strain is of growing interest because of its clinical value in the detection of early myocardial dysfunction and stratifying patient prognosis. Cardiovascular MR imaging techniques are considered reference techniques, especially MR tagging, which remains the most widely available and validated car-diovascular MR modality for myocardial strain quantification. Diabetes not only increases the risk of MI but also increases the mortality associated with the acute event. DM is a strong independent predictor of short and long-term recurrent ischemic events, including mortality, in patients with ACS. Correlation between the GLPSS by speckle tracking echocardiography with traditional echocardiographic indices in diabetic patients with STEMI in 24hrs after primary PCI.
Methods: 30 patients with STEMI (58±8, 9 diabetic, 21 non diabetic) all patients underwent 1ry PCI. Conventional 2D echocardiography to asses LVEF, WMSI, EDV and ESVI and speckle tracking echocardiography to asses LV GLPSS was done within 24hr of 1ry PCI.
Results: All patients with STEMI had low LV avge GLPSS (–10.57±2.67%) with significant between diabetic (–9.00± 2.3%) and non diabetec (–11.2±2.6%) with significant p:0.03, at Avge GLPSS –9.5% all dibetic patients uncontrolled diabetis with HbA1C ³10 with sensitevity 66% and specificity 72% and AUC 0.7, no significant between diabetic and non diabetic patients as regarding LVEDV with p:0.7, LVESV with p:0.4, LVESVI p:0.2 , EF with p:0.6, or WMSI with p:0.7. Significant proportional correlation found between Avg GLS and EF with p:0.01 and significant inverse correlation between Avg GLS and WMSI was found with p:0.04 no significant between Avg GLS and ESVI with p:0.08.